Therapeutic properties of aqueous extracts of leaves and stems bark of Prosopis africana (Guill. & Perr.) Taub. (Fabaceae) used in the management of dental caries

Prosopis africana (Guill. & Perr.) Taub. (Fabaceae) is used in the herbal medicine of Burkina Faso to treat dental caries. This study aims contribute valorization said plant by investigating antioxidant, anti-inflammatory and antibacterial properties aqueous leaves stems extracts.
 The inhibitory activity on lipoxygenase was evaluate effect extracts. antioxidant bots extracts assessed using DPPH radical scavenging, ABTS+ cation decolorization. anti-biofilm evaluated Streptococcus mutans ATCC 25175, Staphylococcus aureus 43300, Pseudomonas aeruginosa PAOI anti-Quorum sensing Chromobacterium CV026.
 Aqueous show highest content phenolic compounds (30,04± 0,59 mgAGE/100 mg extract) while those total flavonoids (3.29 ± 0.53 mgQE/100mg extract). extract stem bark strongest ( IC50 = 4.58±0.07µg/ml for ABTS) , a best Inhibitory action (IC50 13.42 1.26 μg/mL ), 63.6%; at concentration 100µg/ml) without affecting bacterial growth. In addition, this has anti-quorum with an percentage inhibition 53,5%.
 These findings suggested that contain promoted phytomolecules combat caries infections.
 Keywords : Anti-biofilm, Anti-quorum sensing, Lipoxygenase,